Question

Any help on how to create a matrix with M + 1 columns and N + 1 rows where M and N are correspond to the size of the sequences. I need it for alignment of two sequences.

I’ve tried using numpy. But i got fixed size matrix.

Answer 1

[[0. for i in range(m+1)] for j in range(n+1)]

will produce a m+1 by n+1 matrix.

Using a numpy array will likely be faster for many operations, if you use numpy right:

numpy.zeros((m+1, n+1))