Question

Cappuccino is one.

“With Cappuccino, you don’t need to
know HTML. You’ll never write a line
of CSS. You don’t ever have interact
with DOM.”

What other front-end frameworks completely abstract away DOM/HTML/JavaScript/CSS?

Answer 1

Here’s another:
http://qooxdoo.org

They say:

“No HTML, CSS nor DOM knowledge is needed.”

and:

“No HTML has to be used and augmented to define the interface. The qooxdoo developer does not even have to know CSS to style the interface. “