How can we change the shape of a Windows Forms Form? I mean, like totally mangle the thing.
Something like this? And is System.Drawing the best way to go about changing the shape of things, like forms? Or is there something else that I would need to use instead?

I’m not after code or anything, just some helpful references.
MSDN has a reference page on How to: Create Nonrectangular Windows Forms. It walks through the entire process.