I am getting the following error trying to load a basic project template:
Error 12 Could not load the assembly file://\\psf\home\documents\visual studio 2010\Projects\WindowsPhonePivotApplication1\WindowsPhonePivotApplication1\obj\Debug\WindowsPhonePivotApplication1.dll. This assembly may have been downloaded from the Web. If an assembly has been downloaded from the Web, it is flagged by Windows as being a Web file, even if it resides on the local computer. This may prevent it from being used in your project. You can change this designation by changing the file properties. Only unblock assemblies that you trust. See http://go.microsoft.com/fwlink/?LinkId=179545 for more information. WindowsPhonePivotApplication1
I don’t have the Security tab when I try and modify the DLL to unblock the assembly. Any advice?

Did you try copying this assembly locally? Currently it seems to be loaded from a network share. You will need to trust that network location if you want to work this way.
Drive:\WINDOWS\Microsoft.NET\Framework\v2.0.50727\caspol.exe -m -ag 1 -url “file:////\computername\sharename*” FullTrust -exclusive on
Check this KB for details… http://support.microsoft.com/kb/320268/