I have a big website and we converted it to a web application. then again we published the application and get the result files in to another web application and do our own development on top of that. above steps are taken to reduce the build time. it reduced the build time but take long time to the first run. our site containing large number of files. is there any suggessions to reduce the run time. after each and every change we have to wait 5-10 minutes to load the site.
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I think Application Initialization Module will be usefull for you 😉
EDIT
Adding following code solved the problem,