I have a solution with just under 100 projects in it, a mix of C++ and C# (mostly C#). When working in VS2005, the working set of Visual Studio is considerably smaller than that of VS2010.
I was wondering if there are some things that can be turned off, so I can develop in VS2010 under 32-bit OS without running out of memory.
You can try using the Solution Load Manager. It’ll let you mark some of the projects files as load on demand or not load at all. That may help.