I have a two segments AB and CD (in red). These two segments are facing each others. They are not completely parallel but will never be perpendicular to each others either.
From that, I need to find the two normals of these segments (in blue) that oppose each others (i.e. the two normals are outside ABCD). I know how to calculate the normals of the segments but obviously each segment has two normals, and I cannot figure out how to programmatically select the ones I need. Any suggestion?

Calculate the vector v between the midpoints of the two segments, pointing from AB to CD. Now the projection of the desired normal to AB onto v must be negative and the projection of the desired normal to CD onto v must be positive. So just calculate the normals, check against v, and negate the normals if needed to make them satisfy the condition.
Here it is in Python:
Note that I assume the endpoints define lines meeting the conditions in the problem. Nor do I check for the edge case when the lines have the same midpoint; the notion of “outside” doesn’t apply in that case.