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Editorial Team
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Editorial Team
Asked: May 17, 20262026-05-17T14:48:14+00:00 2026-05-17T14:48:14+00:00

I have installed PythonWin installed.. I can read and write to Excel from Python,

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I have installed PythonWin installed..
I can read and write to Excel from Python, not a problem. Not the usage I need.
All examples I have found are more complex than I need. Since, I’m moving away
from Excel, I need a half steps for testing.

Whats the simplest way to fire off python scripts from Excel. I dont need gui.
Usage: On open of xls excute python script. Nothing fancy.

Right now, I simply execute the scripts manually before opening xls.

Private Sub Workbook_Open()

MyPythonScript.pyw ' this is where scripts should go. just one is all I need. 

End Sub
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  1. Editorial Team
    Editorial Team
    2026-05-17T14:48:15+00:00Added an answer on May 17, 2026 at 2:48 pm

    You can use Excel’s Shell function*, e.g.

    Sub RunExternalProg()
    
        Dim return_value As Double
        return_value = Shell("C:\Python26\pythonw.exe C:\my_script.py", vbHide)
        Debug.Print return_value
    
    End Sub
    

    You may need to change the path to the pythonw executable; depending on your setup.

    *Shell runs an executable program and returns a Variant (Double)
    representing the program’s task ID if successful, otherwise it returns zero.

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