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Home/ Questions/Q 815067
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Editorial Team
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Editorial Team
Asked: May 15, 20262026-05-15T01:37:21+00:00 2026-05-15T01:37:21+00:00

I have large file comprising ~100,000 lines. Each line corresponds to a cluster and

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I have large file comprising ~100,000 lines. Each line corresponds to a cluster and each entry within each line is a reference i.d. for another file (protein structure in this case), e.g.

1hgn 1dju 3nmj 8kfn
9opu 7gfb 
4bui

I need to read in the file as a list of lists where each line is a sublist, thus preserving the integrity of the cluster, e.g.

nested_list = [['1hgn', '1dju', '3nmj', '8kfn'], ['9opu', '7gfb'], ['4bui']]

My current code creates a nested list but the entries within each list are a single string and not comma separated. Therefore, I cannot splice the list with indices so easily.

Any help greatly appreciated.

Thanks,
S 🙂

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  1. Editorial Team
    Editorial Team
    2026-05-15T01:37:22+00:00Added an answer on May 15, 2026 at 1:37 am

    Super simple:

    with open('myfile', 'r') as f:
        data = [line.split() for line in f]
    
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