I have written a little define called ensureInMainThread (and I use it quite a bit). However, I’m not sure exactly which user interface methods require being called on the main thread. What about setNeedsDisplay and setNeedsLayout? What is the rule of thumb for methods that need to be called on the main thread in iOS 5.x?
These questions are related (some low quality questions and answers, and some very case specific), but I would like a comprehensive, single good answer:
As of iOS 4.0, some user interface updates can be performed on a background thread:
David Duncan confirms this in his comments here.
Beyond that, pretty much everything else regarding UIKit is not considered threadsafe, so you should make sure you are interacting with it on the main thread in those cases.
As an aside, I do prefer my block-based implementation of a “always run on the main thread” function over the macro you link to, because I like the explicit wrapping of code that needs to be run on the main thread.