I recently started using a black theme for Visual Studio and love it. I would also like it if I could get all the panels to change colour to something more like the Expression suite of programs. Im guessing this is not possible in VS2008, but can it be done in VS2010 since it uses WPF?
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I work at a company that build online training products. We have some good research data that says dark colors in higher frequencies cause less eye strain. While this does’t really answer your question, dark blue with white and yellow text colors seems to be best for extended viewing.