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I want to access some .NET assemblies written in C# from Python code.
A little research showed I have two choices:
What are the trade-offs between both solutions?
If you want to mainly base your code on the .NET framework, I’d highly recommend IronPython vs Python.NET. IronPython is pretty much native .NET – so it just works great when integrating with other .NET langauges.
Python.NET is good if you want to just integrate one or two components from .NET into a standard python application.
There are notable differences when using IronPython – but most of them are fairly subtle. Python.NET uses the standard CPython runtime, so this Wiki page is a relevant discussion of the differences between the two implementations. The largest differences occur in the cost of exceptions – so some of the standard python libraries don’t perform as well in IronPython due to their implementation.