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Home/ Questions/Q 7956139
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Editorial Team
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Editorial Team
Asked: June 4, 20262026-06-04T03:54:24+00:00 2026-06-04T03:54:24+00:00

I’m deploying a Python app on Windows for the first time (Apache & mod_wsgi/Flask/Sqlalchemy).

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I’m deploying a Python app on Windows for the first time (Apache & mod_wsgi/Flask/Sqlalchemy).

I’d like to use pyodbc to get Sqlalchemy talking to mssql.

I was able to install a binary build of pyodbc with no problem, and it works when I use it from the command line. However, mod_wsgi is logging import errors when it hits import pyodbc

This thread on the pyodbc issue tracker describes my issue exactly, and seems to implicate Windows manifests. However, I can’t figure out how to use mt.exe to resolve it.

In PowerShell:

C:\my\site-packages> C:\Program Files\Microsoft SDKs\Windows\v7.1\Bin\mt.exe 
-inputresource:c:\Windows\SysWOW64\python27.dll;#2 -manifest 
-outputresource:pyodbc.pyd#2'

mt.exe : command line error c10100a9: Some operation on the input manifests must
be specified (even if it is just to pipe the input to the output).
Use the /? option for help on usage and samples.`

In cmd:

C:\my\site-packages>"C:\Program Files\Microsoft SDKs"\Windows\v7.1\Bin\mt.exe 
-inputresource:C:\Windows\SysWOW64\python27.dll#2 -outputresource:pyodbc.pyd#2

mt.exe : general error c101008c: Failed to read the manifest from the resource 
of file "C:\Windows\SysWOW64\python27.dll#2". The system cannot find the file 
specified.

What am I doing wrong?!

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  1. Editorial Team
    Editorial Team
    2026-06-04T03:54:26+00:00Added an answer on June 4, 2026 at 3:54 am

    I’m the author of the thread on the pyodbc issue tracker.

    Unless I’m missing something it looks like the file “C:\Windows\SysWOW64\python27.dll” doesn’t exist. Maybe you have a version other than 2.7?

    Otherwise, make sure you have installed the official windows packages for python and verify that importing pyodbc succeeds with that version. If it does, you should be able to substitute the path to your local python.dll (e.g. python27.dll) from the python installation root or elsewhere.

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