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Home/ Questions/Q 5946551
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Editorial Team
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Editorial Team
Asked: May 22, 20262026-05-22T16:50:20+00:00 2026-05-22T16:50:20+00:00

I’m new to Python, and I need to do a parsing exercise. I got

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I’m new to Python, and I need to do a parsing exercise. I got a file, and I need to parse it (just the headers), but after the process, i need to keep the file the same format, the same extension, and at the same place in disk, but only with the differences of new headers..

I tried this code…

for line in open ('/home/name/db/str/dir/numbers/str.phy'):
    if line.startswith('ENS'):
        linepars = re.sub ('ENS([A-Z]+)0+([0-9]{6})','\\1\\2',line)
        print linepars

..and it does the job, but I don’t know how to “overwrite” the file with the new parsing.

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1 Answer

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  1. Editorial Team
    Editorial Team
    2026-05-22T16:50:21+00:00Added an answer on May 22, 2026 at 4:50 pm

    The easiest way, but not the most efficient (by far, and especially for long files) would be to rewrite the complete file.

    You could do this by opening a second file handle and rewriting each line, except in the case of the header, you’d write the parsed header. For example,

    fr = open('/home/name/db/str/dir/numbers/str.phy')
    fw = open('/home/name/db/str/dir/numbers/str.phy.parsed', 'w') # Name this whatever makes sense
    
    for line in fr:
        if line.startswith('ENS'):
            linepars = re.sub ('ENS([A-Z]+)0+([0-9]{6})','\\1\\2',line)
            fw.write(linepars)
        else:
            fw.write(line)
    
    fw.close()
    fr.close()
    

    EDIT: Note that this does not use readlines(), so its more memory efficient. It also does not store every output line, but only one at a time, writing it to file immediately.

    Just as a cool trick, you could use the with statement on the input file to avoid having to close it (Python 2.5+):

    fw = open('/home/name/db/str/dir/numbers/str.phy.parsed', 'w') # Name this whatever makes sense
    
    with open('/home/name/db/str/dir/numbers/str.phy') as fr:
        for line in fr:
            if line.startswith('ENS'):
                linepars = re.sub ('ENS([A-Z]+)0+([0-9]{6})','\\1\\2',line)
                fw.write(linepars)
            else:
                 fw.write(line)
    
    fw.close()
    

    P.S. Welcome 🙂

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