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Home/ Questions/Q 7990109
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Editorial Team
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Editorial Team
Asked: June 4, 20262026-06-04T12:54:47+00:00 2026-06-04T12:54:47+00:00

I’m trying to compute Wald tests for interaction terms in a generalized additive model

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I’m trying to compute Wald tests for interaction terms in a generalized additive model (gam in mgcv package) using R. The documentation for regTermTest says that the function takes a model with coef and vcov methods, but putting a gam model in doesn’t seem to work. How can I get this method to work? If it can’t be done, is there another simple way to compute the same values in R?

lm model works

model <- lm(sysbp~pmper10*se_race4,data=mesa)
regTermTest(model,"pmper10:se_race4")
# Wald test for pmper10:se_race4
# in lm(formula = sysbp ~ pmper10 * se_race4, data = mesa)
# F =  3.940545  on  3  and  43621  df: p= 0.0080253 

but gam model does not

model <- gam(sysbp~pmper10*se_race4,data=mesa)
regTermTest(model,"pmper10:se_race4")
# Error in solve.default(V) : 'a' is 0-diml
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  1. Editorial Team
    Editorial Team
    2026-06-04T12:54:48+00:00Added an answer on June 4, 2026 at 12:54 pm

    This will work if you use the library gam but not mgcv.

    The regTermTest function relies on extracting the 'assign' attribute from the model matrix for a given model.


    aa <- attr(model.matrix(model), "assign")[okbeta]

    This object aa is used to construct the indices when creating V

    A gam object from the package mgcv does not have this attribute. Using the example from survey::regTermTest

    data(esoph)
     model1 <- glm(cbind(ncases, ncontrols) ~ agegp + tobgp * 
       alcgp, data = esoph, family = binomial())
    
    
    regTermTest(model1,"tobgp")
    

    If we use the package gam

    library(gam)
     model2 <- gam(cbind(ncases, ncontrols) ~ agegp + tobgp * 
       alcgp, data = esoph, family = binomial())
    
     regTermTest(model2,"tobgp")
    

    Gives the output

    Wald test for tobgp
       in gam(formula = cbind(ncases, ncontrols) ~ agegp + tobgp * alcgp, 
         family = binomial(), data = esoph)
      F =  3.961947  on  3  and  67  df: p= 0.011609 
    

    While

    library(mgcv)
    
    model3 <- gam(cbind(ncases, ncontrols) ~ agegp + tobgp * 
       alcgp, data = esoph, family = binomial())
    
    
     regTermTest(model3,"tobgp")
    

    Gives the error reported by the OP.

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