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Editorial Team
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Editorial Team
Asked: May 11, 20262026-05-11T22:25:20+00:00 2026-05-11T22:25:20+00:00

I’m trying to do office 2003 interop using C# ASP.NET on a server running

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I’m trying to do office 2003 interop using C# ASP.NET on a server running Windows 2003 64 bit (I’m running IIS in 32bit mode though) and getting error messages like:

The machine-default permission settings do not grant Local Activation permission for the COM Server application with CLSID
{00024500-0000-0000-C000-000000000046} to the user domain\username SID (S-X-X-XX-XXX-XXXX-XXX-XXXXX). This security permission can be modified using the Component Services administrative tool.

Does anybody know what I need to change to get this working? Thanks if you can help.

EDIT – This was working fine on a 32bit server.

EDIT 2 – Nobody seems to like this but I’m not sure there’s any other way given our requirements. If you can think of one, I’ve opened another question alternative-to-office-interop-for-document-generation

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  1. Editorial Team
    Editorial Team
    2026-05-11T22:25:20+00:00Added an answer on May 11, 2026 at 10:25 pm

    I’ve found the answer. Search for the problem guid in regedit. You’ll then come across a key that contains two values – the name of the component and it’s guid in component services.

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