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There have been some questions and answers here on stackoverflow, but no one asked if it’s a good solution to run django on IIS.
Any experience is welcome, both good and bad.
One thing I know is that Django has no official support for IronPython – just CPython and Jython. In addition, PIL – which provides Django’s support for image fields – does not natively support IronPython, though the ironclad project could help with that. (Caveat: I have never actually used IronPython, this is just based on research.)
My recommendation would be to use a standard Python interpreter to run Django and use either FastCGI or isapi_wsgi to connect it to your IIS, as Django has more support for FastCGI and WSGI.