Very straightforward:
Is it possible to prevent the browser from scrolling when a user pressed arrow keys?
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Very straightforward: Yes, but don’t do it.
Changing fundamental operation of how a browser operates just confuses or angers users, and makes the whole experience less user-friendly. The user should have ultimate control of the way his or her browser functions, not you. This is similar to blocking menu items from being accessed, or removing context menus etc.