What are the valid ways to write (hopefully native) C++ applications with GUI in VS 2010?
I remember some 10 years ago I was using MFC, any big changes today?
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If you want to stay with Native API then MFC is still a good choice or plain Win32 API.
There are new controls like the ribbon control introduced in VS2010. There’s a tutorial on native development with VS2010 on MSDN. There are also a lot of C++0x features available to your native program if you’re using VS2010.
Qt is another good choice even if you aren’t going cross platform but you won’t be using VS 2010 most likely in that case. The licensing is now free for commercial use with LGPL.
If you are going to use a newer framework like WPF from Microsoft then you will need to use a managed language (.NET). Another choice is Silverlight for both web and apps. Silverlight apps have the advantage that you can get them to work even on Mac if they have Silverlight installed. Winforms is still easy to code but mostly superseded by WPF.
Unless you have good reason to do so, you can develop much faster with a framework like WPF instead of MFC. Even if you don’t know a managed language. (If you don’t go straight to C# instead of C++/CLI). WPF also offers GPU acceleration.