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Home/ Questions/Q 646697
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Editorial Team
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Editorial Team
Asked: May 13, 20262026-05-13T21:38:27+00:00 2026-05-13T21:38:27+00:00

When I try to open a file in write mode with the following code:

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When I try to open a file in write mode with the following code:

packetFile = open("%s/%s/%s/%s.mol2" % ("dir", "dir2", "dir3", "some_file"), "w")

I get the following error:

IOError: [Errno 2] No such file or directory: 'dir/dir2/dir3/some_file.mol2'

The w mode should create the file if it doesn’t exist, right? So how can this error ever occur?

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1 Answer

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  1. Editorial Team
    Editorial Team
    2026-05-13T21:38:28+00:00Added an answer on May 13, 2026 at 9:38 pm

    You’ll see this error if the directory containing the file you’re trying to open does not exist, even when trying to open the file in w mode.

    Since you’re opening the file with a relative path, it’s possible that you’re confused about exactly what that directory is. Try putting a quick print to check:

    import os
    
    curpath = os.path.abspath(os.curdir)
    packet_file = "%s/%s/%s/%s.mol2" % ("dir", "dir2", "dir3", "some_file")
    print "Current path is: %s" % (curpath)
    print "Trying to open: %s" % (os.path.join(curpath, packet_file))
    
    packetFile = open(packet_file, "w")
    
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