I am leaning towards uwsgi+nginx for my Django app, can anyone share the best method for starting up my uwsgi processes? Does anyone have experience tuning uwsgi?
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Launchd on OSX
Upstart/init on the unices.
uwsgi also has its own process manager, so you can just run that as well.
Tuning:
Check the mailing list, for advice on your particular requirements. Uwsgi is amazing, it is a complete deploy solution.
Nginx above 0.8.40 will build the uwsgi bindings by default, Build nginx, build uwsgi and you are golden.